Asbestos Abatement
Hazard Summary
Asbestos has been used in building materials, paper products, plastics,
and other products. Exposure mainly occurs in indoor air where it
may be released from these materials. Effects on the lung are a
major health concern from asbestos, as chronic (long-term) exposure to
asbestos in humans via inhalation can result in a lung disease termed
asbestosis. Asbestosis is characterized by shortness of breath
and cough and may lead to severe impairment of respiratory
function. Cancer is also a major concern from asbestos exposure,
as inhalation exposure can cause lung cancer and mesothelioma (a rare
cancer of the thin membranes lining the abdominal cavity and
surrounding internal organs), and possibly gastrointestinal cancers in
humans. EPA has classified asbestos as a Group A, known human
carcinogen.
Please Note: The main sources of information for this fact sheet are
EPA's Integrated Risk Information System (IRIS),
which contains information on the carcinogenic effects of asbestos
including the unit cancer risk for inhalation exposure, and the Agency
for Toxic Substances and Disease Registry's (ATSDR's) Toxicological Profile
for Asbestos.
Uses
- The main uses of asbestos are in building materials, paper
products, asbestos-cement products, friction products, textiles,
packings and gaskets, and asbestos-reinforced plastics. (1)
- Asbestos use in the United States is currently decreasing. (1)
Sources and Potential Exposure
- Airborne exposure to asbestos may occur through the erosion of
natural deposits in asbestos-bearing rocks, from a variety of
asbestos-related industries, or from clutches and brakes on cars and
trucks. The concentrations in outdoor air are highly variable. (1)
- Asbestos has been detected in indoor air, where it is released
from a variety of building materials such as insulation and ceiling and
floor tiles. It is only released, however, when these building
materials are damaged or disintegrate. Typical concentrations in
indoor air range from 1 to 200 nanograms per cubic meter (ng/m3)
(0.000001 to 0.002 milligrams per cubic meter (mg/m3)). (1)
- Asbestos may be released to water from a number of sources,
including erosion of natural deposits, corrosion from asbestos-cement
pipes, and disintegration of asbestos roofing materials with subsequent
transport into sewers. (1)
Assessing Personal Exposure
- It is possible to test for the presence of asbestos fibers in
urine, feces, or mucus. In addition, a chest X-ray, although it
cannot detect the asbestos fibers themselves, can detect early signs of
lung disease caused by asbestos. (1)
Health Hazard Information
Acute Effects:
- No studies were located on the acute (short-term) toxicity of
asbestos in animals or humans. (1-4)
Chronic Effects (Noncancer):
- Chronic inhalation exposure to asbestos in humans can lead to a
lung disease called asbestosis, which is a diffuse fibrous scarring of
the lungs. Symptoms of asbestosis include shortness of breath,
difficulty in breathing, and coughing. Asbestosis is a
progressive disease, i.e., the severity of symptoms tends to increase
with time, even after the exposure has stopped. In severe cases,
this disease can lead to death, due to impairment of respiratory
function. (1,2)
- Other effects from asbestos exposure via inhalation in humans
include pulmonary hypertension and immunological effects. (1,2)
- Feeding studies in animals exposed to high doses of asbestos
have not detected any evidence of adverse toxic effects. (1,2)
- EPA has not established a Reference Concentration (RfC)
or a Reference Dose (RfD)
for asbestos. (5)
Reproductive/Developmental Effects:
- No studies were located on the developmental or reproductive
effects of asbestos in animals or humans via inhalation. (1,2,3)
- Birth defects were not noted in the offspring of animals exposed
to asbestos in the diet during pregnancy. (1)
- No effects on fertility were observed in animals exposed to
asbestos in the diet during breeding, pregnancy, and lactation. (1)
Cancer Risk:
- A large number of occupational studies have reported that
exposure to asbestos via inhalation can cause lung cancer and
mesothelioma (a rare cancer of the membranes lining the abdominal
cavity and surrounding internal organs). (1,2,3)
- Individuals who smoke and are also exposed to asbestos have a
greater than additive increased risk of developing lung cancer. (1)
- Several occupational studies have reported an increase in
gastrointestinal cancer from inhalation exposure to asbestos and
subsequent oral ingestion. (1,2)
- Long- and intermediate-range asbestos fibers (>5 micrometers
(µm)) appear to be more carcinogenic than short fibers (<5
µm). (1)
- Several epidemiological studies have found an association
between asbestos in drinking water and cancer of the esophagus,
stomach, and intestines; however confounding factors and the short
followup time relative to the long latent period for tumor formation
make it difficult to interpret the results. (1,5)
- A series of large-scale lifetime feeding studies in animals
reported that intermediate-range asbestos fibers increased the
incidence of a benign tumor of the large intestine in male rats, while
short-range asbestos fibers showed no significant increase in tumor
incidence. (1,5)
- EPA considers asbestos to be a human carcinogen (cancer-causing
agent) and has ranked it in EPA's Group A. (5)
- EPA uses mathematical models, based on human and animal studies,
to estimate the probability of a person developing cancer from
breathing air containing a specified concentration of a chemical. EPA
calculated an inhalation unit risk estimate of 2.3 × 10-1
(fibers/cm3)-1. EPA estimates that, if an
individual were to continuously breathe air containing asbestos at an
average of 0.000004 fibers/cm3 over his or her entire
lifetime, that person would theoretically have no more than a
one-in-a-million increased chance of developing cancer as a direct
result of breathing air containing this chemical. Similarly, EPA
estimates that breathing air containing 0.00004 fibers/cm3
would result in not greater than a one-in-a-hundred thousand increased
chance of developing cancer, and air containing 0.0004 fibers/cm3
would result in not greater than a one-in-ten-thousand increased chance
of developing cancer. (5)
Asbestos Physical Properties
- Asbestos is the name applied to a group of six different
minerals that occur naturally in the environment. (1)
- The most common mineral type is white, but others may be blue,
gray, or brown. (1)
- These minerals are made up of long, thin fibers that are
somewhat similar to fiberglass. (1)
- Asbestos is neither volatile nor soluble; however, small fibers
may occur in suspension in both air and water. (1)
Health Data from Inhalation Exposure
ACGIH TLV--American Conference of Governmental and Industrial
Hygienists' threshold limit value expressed as a time-weighted average;
the concentration of a substance to which most workers can be exposed
without adverse effects.
NIOSH REL--National Institute of Occupational Safety and
Health's recommended exposure limit; NIOSH-recommended exposure limit
for an 8- or 10-h time-weighted-average exposure and/or ceiling.
OSHA PEL--Occupational Safety and Health Administration's
permissible exposure limit expressed as a time-weighted average; the
concentration of a substance to which most workers can be exposed
without adverse effect averaged over a normal 8-h
workday or a 40-h workweek.
The health and regulatory values cited in this factsheet were
obtained in December 1999.
a Health numbers are toxicological
numbers from animal testing or risk assessment values developed by EPA.
b Regulatory numbers are values that have
been incorporated in Government regulations, while advisory numbers are
nonregulatory values provided by the Government or other groups as
advice. OSHA numbers are regulatory, whereas NIOSH and ACGIH
numbers are advisory.
Asbestos Abatement References
- Agency for Toxic Substances and Disease
Registry (ATSDR). Toxicological Profile for Asbestos (Draft).
U.S. Public Health Service, U.S. Department of Health and Human
Services, Atlanta, GA. 1995.
- E.J. Calabrese and E.M. Kenyon. Air Toxics
and Risk Assessment. Lewis Publishers, Chelsea, MI. 1991.
- U.S. Department of Health and Human Services.
Hazardous Substances Data Bank (HSDB,
online database). National Toxicology Information Program, National
Library of Medicine, Bethesda, MD. 1993.
- U.S. Department of Health and Human Services.
Registry of Toxic Effects of Chemical Substances (RTECS, online
database). National Toxicology Information Program, National Library of
Medicine, Bethesda, MD. 1993.
- U.S. Environmental Protection Agency. Integrated Risk
Information System (IRIS) on Asbestos. National Center for
Environmental Assessment, Office of Research and Development,
Washington, DC. 1999
- National Institute for Occupational Safety and
Health (NIOSH). Pocket
Guide to Chemical Hazards. U.S. Department of Health and Human
Services, Public Health Service, Centers for Disease Control and
Prevention. Cincinnati, OH. 1997.
- Occupational Safety and Health Administration
(OSHA). Occupational Safety and Health Standards, Toxic and Hazardous
Substances. Code of Federal Regulations. 29 CFR 1910.1001. 1998.
- American Conference of Governmental Industrial
Hygienists (ACGIH). 1999 TLV's and BEIs. Threshold Limit Values for
Chemical Substances and Physical Agents, Biological Exposure Indices.
Cincinnati, OH. 1999.